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Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties

[Image: see text] Polyguanidinium oxanorbornene (PGON) was synthesized from norbornene monomers via ring-opening metathesis polymerization. This polymer was observed to be strongly antibacterial against Gram-negative and Gram-positive bacteria as well as nonhemolytic against human red blood cells. T...

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Bibliografski detalji
Glavni autori: Gabriel, Gregory J., Madkour, Ahmad E., Dabkowski, Jeffrey M., Nelson, Christopher F., Nüsslein, Klaus, Tew, Gregory N.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2008
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646885/
https://ncbi.nlm.nih.gov/pubmed/18850741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm800855t
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