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The effects of a ketogenic diet on ATP concentrations and the number of hippocampal mitochondria in Aldh5a1(−/−) mice
BACKGROUND: Succinic semialdehyde dehydrogenase (SSADH) deficiency is an inborn error of GABA metabolism characterized clinically by ataxia, psychomotor retardation and seizures. A mouse model of SSADH deficiency, the Aldh5a1(−/−) mouse, has been used to study the pathophysiology and treatment of th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646796/ https://ncbi.nlm.nih.gov/pubmed/19168117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2008.12.005 |
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