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The effects of a ketogenic diet on ATP concentrations and the number of hippocampal mitochondria in Aldh5a1(−/−) mice

BACKGROUND: Succinic semialdehyde dehydrogenase (SSADH) deficiency is an inborn error of GABA metabolism characterized clinically by ataxia, psychomotor retardation and seizures. A mouse model of SSADH deficiency, the Aldh5a1(−/−) mouse, has been used to study the pathophysiology and treatment of th...

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Autori principali: Nylen, Kirk, Velazquez, Jose Luis Perez, Sayed, Venus, Gibson, K. Michael, Burnham, W.M., Snead, O. Carter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646796/
https://ncbi.nlm.nih.gov/pubmed/19168117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2008.12.005
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