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A new plasmid vector for DNA delivery using lactococci

BACKGROUND: The use of food-grade lactococci as bacterial carriers to DNA delivery into epithelial cells is a new strategy to develop live oral DNA vaccine. Our goal was to develop a new plasmid, named pValac, for antigen delivery for use in lactococci. The pValac plasmid was constructed by the fusi...

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Detalhes bibliográficos
Main Authors: Guimarães, Valeria, Innocentin, Sylvia, Chatel, Jean-Marc, Lefèvre, François, Langella, Philippe, Azevedo, Vasco, Miyoshi, Anderson
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646724/
https://ncbi.nlm.nih.gov/pubmed/19208231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-7-4
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