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Distinct Flippases Translocate Glycerophospholipids and Oligosaccharide Diphosphate Dolichols across the Endoplasmic Reticulum
[Image: see text] Transbilayer movement, or flip-flop, of lipids across the endoplasmic reticulum (ER) is required for membrane biogenesis, protein glycosylation, and GPI anchoring. Specific ER membrane proteins, flippases, are proposed to facilitate lipid flip-flop, but no ER flippase has been bioc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2008
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646664/ https://ncbi.nlm.nih.gov/pubmed/18597486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800723n |
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