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Specific transbilayer translocation of dolichol-linked oligosaccharides by an endoplasmic reticulum flippase

The oligosaccharide donor for protein N-glycosylation, Glc(3)Man(9)GlcNAc(2)-PP-dolichol, is synthesized via a multistep pathway that starts on the cytoplasmic face of the endoplasmic reticulum (ER) and ends in the lumen where the glycosylation reaction occurs. This necessitates transbilayer translo...

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Detalhes bibliográficos
Main Authors: Sanyal, Sumana, Menon, Anant K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630073/
https://ncbi.nlm.nih.gov/pubmed/19129492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810225106
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