Pharmacological Manipulation of the RAR/RXR Signaling Pathway Maintains the Repopulating Capacity of Hematopoietic Stem Cells in Culture

The retinoid X receptor (RXR) contributes to the regulation of diverse biological pathways via its role as a heterodimeric partner of several nuclear receptors. However, RXR has no established role in the regulation of hematopoietic stem cell (HSC) fate. In this study, we sought to determine whether...

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Detalhes bibliográficos
Main Authors: Safi, Rachid, Muramoto, Garrett G., Salter, Alice B., Meadows, Sarah, Himburg, Heather, Russell, Lauren, Daher, Pamela, Doan, Phuong, Leibowitz, Mark D., Chao, Nelson J., McDonnell, Donald P., Chute, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646618/
https://ncbi.nlm.nih.gov/pubmed/19106195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0121
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