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Releasing the spindle assembly checkpoint without tension
Eukaryotic cells have evolved a spindle assembly checkpoint (SAC) that facilitates accurate genomic segregation during mitosis by delaying anaphase onset in response to errors in kinetochore microtubule attachment. In contrast to the well-studied molecular mechanism by which the SAC blocks anaphase...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646545/ https://ncbi.nlm.nih.gov/pubmed/19193624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812016 |
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