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Releasing the spindle assembly checkpoint without tension

Eukaryotic cells have evolved a spindle assembly checkpoint (SAC) that facilitates accurate genomic segregation during mitosis by delaying anaphase onset in response to errors in kinetochore microtubule attachment. In contrast to the well-studied molecular mechanism by which the SAC blocks anaphase...

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Detalhes bibliográficos
Main Authors: McEwen, Bruce F., Dong, Yimin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646545/
https://ncbi.nlm.nih.gov/pubmed/19193624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812016
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