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Lean Phenotype and Resistance to Diet-Induced Obesity in Vitamin D Receptor Knockout Mice Correlates with Induction of Uncoupling Protein-1 in White Adipose Tissue

Increased adiposity is a feature of aging in both mice and humans, but the molecular mechanisms underlying age-related changes in adipose tissue stores remain unclear. In previous studies, we noted that 18-month-old normocalcemic vitamin D receptor (VDR) knockout (VDRKO) mice exhibited atrophy of th...

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Autors principals: Narvaez, Carmen J., Matthews, Donald, Broun, Emily, Chan, Michelle, Welsh, JoEllen
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646525/
https://ncbi.nlm.nih.gov/pubmed/18845643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1118
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