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High Dietary Vitamin D Prevents Hypocalcemia and Osteomalacia in CYP27B1 Knockout Mice

Mice lacking 25-hydroxycholecalciferol [25(OH)D]-1α-hydroxylase (CYP27B1) are growth retarded, hypocalcemic, and have poor bone mineralization. We tested whether high dietary cholecalciferol (VD3) could exert effects in the absence of CYP27B1 in vivo. Weanling male wild-type (WT) and CYP27B1 knockou...

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Bibliografiske detaljer
Main Authors: Rowling, Matthew J., Gliniak, Christy, Welsh, JoEllen, Fleet, James C.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553887/
https://ncbi.nlm.nih.gov/pubmed/18029472
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