The Association of ENPP1 K121Q with Diabetes Incidence Is Abolished by Lifestyle Modification in the Diabetes Prevention Program

Context: Insulin resistance is an important feature of type 2 diabetes. Ectoenzyme nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) inhibits insulin signaling, and a recent meta-analysis reported a nominal association between the Q allele in the K121Q (rs1044498) single nucleotide polymorphism...

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Main Authors: Moore, Allan F., Jablonski, Kathleen A., Mason, Clinton C., McAteer, Jarred B., Arakaki, Richard F., Goldstein, Barry J., Kahn, Steven E., Kitabchi, Abbas E., Hanson, Robert L., Knowler, William C., Florez, Jose C.
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2009
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646511/
https://ncbi.nlm.nih.gov/pubmed/19017751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-1583
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