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The Association of ENPP1 K121Q with Diabetes Incidence Is Abolished by Lifestyle Modification in the Diabetes Prevention Program

Context: Insulin resistance is an important feature of type 2 diabetes. Ectoenzyme nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) inhibits insulin signaling, and a recent meta-analysis reported a nominal association between the Q allele in the K121Q (rs1044498) single nucleotide polymorphism...

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Detalhes bibliográficos
Main Authors: Moore, Allan F., Jablonski, Kathleen A., Mason, Clinton C., McAteer, Jarred B., Arakaki, Richard F., Goldstein, Barry J., Kahn, Steven E., Kitabchi, Abbas E., Hanson, Robert L., Knowler, William C., Florez, Jose C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646511/
https://ncbi.nlm.nih.gov/pubmed/19017751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-1583
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