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Annotating genomes with massive-scale RNA sequencing
Next generation technologies enable massive-scale cDNA sequencing (so-called RNA-Seq). Mainly because of the difficulty of aligning short reads on exon-exon junctions, no attempts have been made so far to use RNA-Seq for building gene models de novo, that is, in the absence of a set of known genes a...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646279/ https://ncbi.nlm.nih.gov/pubmed/19087247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-12-r175 |
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