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O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors
Protein O-fucosyltransferase 1 (Pofut1) transfers fucose to serine or threonine on proteins, including Notch receptors, that contain EGF repeats with a particular consensus sequence. Here we demonstrate that agrin is O-fucosylated in a Pofut1-dependent manner, and that this glycosylation can regulat...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646263/ https://ncbi.nlm.nih.gov/pubmed/18775496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.07.026 |
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