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Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation
Agrin is thought to be the nerve-derived factor that initiates acetylcholine receptor (AChR) clustering at the developing neuromuscularjunction. We have investigated the signaling pathway in mouse C2 myotubes and report that agrin induces a rapid but transient tyrosine phosphorylation of the AChR be...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2120739/ https://ncbi.nlm.nih.gov/pubmed/8603924 |
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