Clinical Utility of Genotyping the 677C>T Variant of Methylenetetrahydrofolate Reductase in Humans Is Decreased in the Post-Folic Acid Fortification Era

Moderate hyperhomocysteinemia is associated with many diseases. Major factors affecting plasma total homocysteine (tHcy) concentrations include folate concentrations and polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene. Because U.S.-mandated fortification of grain products with...

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Bibliografiska uppgifter
Huvudupphovsmän: Tsai, Michael Y., Loria, Catherine M., Cao, Jing, Kim, Yongin, Siscovick, David, Schreiner, Pamela J., Hanson, Naomi Q.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Nutrition 2009
Ämnen:
Biochemical, Molecular, and Genetic Mechanisms
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646209/
https://ncbi.nlm.nih.gov/pubmed/19056652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.108.096511
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