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BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation
Bloom syndrome (BS) is a rare genetic disorder characterized by genomic instability and a high predisposition to cancer. The gene defective in BS, BLM, encodes a member of the RecQ family of 3′–5′ DNA helicases, and is proposed to function in recombinational repair during DNA replication. Here, we h...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646154/ https://ncbi.nlm.nih.gov/pubmed/19165145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.298 |
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