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Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J

A new Ginkgo biloba extract P8A (TTL), 70% enriched with terpene trilactones, prevents Aβ(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices. This neuroprotective effect is attributed in large part to ginkgolide J that completely replicates the effect of...

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Autors principals: Vitolo, Ottavio, Gong, Bing, Cao, Zixuan, Ishii, Hideki, Jaracz, Stanislav, Nakanishi, Koji, Arancio, Ottavio, Dzyuba, Sergei V., Lefort, Roger, Shelanski, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646106/
https://ncbi.nlm.nih.gov/pubmed/17640772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.05.025
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