Low Intensity Shear Stress Increases Endothelial ELR(+) CXC Chemokine Production via a Focal Adhesion Kinase-p38β MAPK-NF-κB Pathway

CXC chemokines with a glutamate-leucine-arginine (ELR) tripeptide motif (ELR(+) CXC chemokines) play an important role in leukocyte trafficking into the tissues. For reasons that are not well elucidated, circulating leukocytes are recruited into the tissues mainly in small vessels such as capillarie...

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Autori principali: Shaik, Sadiq S., Soltau, Thomas D., Chaturvedi, Gaurav, Totapally, Balagangadhar, Hagood, James S., Andrews, William W., Athar, Mohammad, Voitenok, Nikolai N., Killingsworth, Cheryl R., Patel, Rakesh P., Fallon, Michael B., Maheshwari, Akhil
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Mechanisms of Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645838/
https://ncbi.nlm.nih.gov/pubmed/19117939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807205200
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