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Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein

The cDNAs of two new human membrane-associated aspartic proteases, memapsin 1 and memapsin 2, have been cloned and sequenced. The deduced amino acid sequences show that each contains the typical pre, pro, and aspartic protease regions, but each also has a C-terminal extension of over 80 residues, wh...

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Bibliografiset tiedot
Päätekijät: Lin, Xinli, Koelsch, Gerald, Wu, Shili, Downs, Debbie, Dashti, Azar, Tang, Jordan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC26455/
https://ncbi.nlm.nih.gov/pubmed/10677483
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