Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein
The cDNAs of two new human membrane-associated aspartic proteases, memapsin 1 and memapsin 2, have been cloned and sequenced. The deduced amino acid sequences show that each contains the typical pre, pro, and aspartic protease regions, but each also has a C-terminal extension of over 80 residues, wh...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10677483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.4.1456 |
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