Generation of Anaphylatoxins by Human β-Tryptase from C3, C4, and C5

Both mast cells and complement participate in innate and acquired immunity. The current study examines whether β-tryptase, the major protease of human mast cells, can directly generate bioactive complement anaphylatoxins. Important variables included pH, monomeric vs tetrameric forms of β-tryptase,...

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Autores principales: Fukuoka, Yoshihiro, Xia, Han-Zhang, Sanchez-Muñoz, Laura B., Dellinger, Anthony L., Escribano, Luis, Schwartz, Lawrence B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645414/
https://ncbi.nlm.nih.gov/pubmed/18424754
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