Cloning and preliminary pharmacological characterization of the anaphylatoxin C5a receptor in the rabbit

1. The rabbit receptor for C5a was cloned from a genomic library and found to be 79.5% identical to the human homologue, the highest degree of similarity found so far in nonprimate laboratory animals. 2. The rabbit C5a receptor stably expressed in RBL cells binds human (125)I-C5a (2 nM). Unlabelled...

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Bibliografiske detaljer
Main Authors: Bachvarov, Dimcho R, Houle, Steeve, Bachvarova, Magdalena, Bouthillier, Johanne, St-Pierre, Serge A, Fukuoka, Yoshihiro, Ember, Julia A, Marceau, François
Format: Artigo
Sprog:Inglês
Udgivet: 1999
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571653/
https://ncbi.nlm.nih.gov/pubmed/10510441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702812
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