A-RAF Kinase Functions in ARF6 Regulated Endocytic Membrane Traffic

BACKGROUND: RAF kinases direct ERK MAPK signaling to distinct subcellular compartments in response to growth factor stimulation. METHODOLOGY/PRINCIPAL FINDINGS: Of the three mammalian isoforms A-RAF is special in that one of its two lipid binding domains mediates a unique pattern of membrane localiz...

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Bibliographic Details
Main Authors: Nekhoroshkova, Elena, Albert, Stefan, Becker, Matthias, Rapp, Ulf R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645234/
https://ncbi.nlm.nih.gov/pubmed/19247477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004647
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