Estrogen Receptor Genotypes Influence Hot Flash Prevalence and Composite Score Before and After Tamoxifen Therapy

PURPOSE: Hot flashes are common and frequently lead to drug discontinuation among women prescribed tamoxifen. We determined whether genetic polymorphisms in estrogen receptors (ESRs) α and β (ESR1 and ESR2, respectively) are associated with tamoxifen-induced hot flashes. PATIENTS AND METHODS: We det...

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Detalhes bibliográficos
Principais autores: Jin, Yan, Hayes, Daniel F., Li, Lang, Robarge, Jason D., Skaar, Todd C., Philips, Santosh, Nguyen, Anne, Schott, Anne, Hayden, Jill, Lemler, Suzanne, Storniolo, Anna Maria, Flockhart, David A., Stearns, Vered
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2008
Assuntos:
Breast Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645113/
https://ncbi.nlm.nih.gov/pubmed/19018086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.16.8377
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