Striatal 5-HT(1A) receptor stimulation reduces D1 receptor-induced dyskinesia and improves movement in the hemiparkinsonian rat

Convergent evidence suggests that serotonin 5-HT(1A) receptor (5-HT(1A)R) agonists reduce L-DOPA-induced dyskinesia by auto-regulating aberrant release of L-DOPA-derived dopamine (DA) from raphestriatal neurons. However, recent findings indicate that 5-HT(1A)R stimulation also modifies D1 receptor (...

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Bibliografiset tiedot
Päätekijät: Dupre, Kristin B., Eskow, Karen L., Barnum, Christopher J., Bishop, Christopher
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645076/
https://ncbi.nlm.nih.gov/pubmed/18824001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.08.031
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