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Striatal 5-HT(1A) receptor stimulation reduces D1 receptor-induced dyskinesia and improves movement in the hemiparkinsonian rat
Convergent evidence suggests that serotonin 5-HT(1A) receptor (5-HT(1A)R) agonists reduce L-DOPA-induced dyskinesia by auto-regulating aberrant release of L-DOPA-derived dopamine (DA) from raphestriatal neurons. However, recent findings indicate that 5-HT(1A)R stimulation also modifies D1 receptor (...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645076/ https://ncbi.nlm.nih.gov/pubmed/18824001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.08.031 |
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