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Enhanced cortisol production rates, free cortisol, and 11β-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss

Controversy exists as to whether endogenous cortisol production is associated with visceral obesity and insulin resistance in humans. We therefore quantified cortisol production and clearance rates, abdominal fat depots, insulin sensitivity, and adipocyte gene expression in a cohort of 24 men. To te...

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Detalhes bibliográficos
Main Authors: Purnell, Jonathan Q., Kahn, Steven E., Samuels, Mary H., Brandon, David, Loriaux, D. Lynn, Brunzell, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645022/
https://ncbi.nlm.nih.gov/pubmed/19050176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90769.2008
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