A SIMPLE ONE-STEP METHOD FOR THE PREPARATION OF HIV-1 ENVELOPE GLYCOPROTEIN IMMUNOGENS BASED ON A CD4 MIMIC PEPTIDE

To counteract the problems associated with the purification of HIV envelopes, we developed a new purification method exploiting the high affinity of a peptide mimicking CD4 towards the viral glycoprotein. This miniCD4 was used as a ligand in affinity chromatography and allowed the separation in one...

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Bibliografiske detaljer
Main Authors: Martin, Grégoire, Sun, Yide, Heyd, Bernadette, Combes, Olivier, Ulmer, Jeffrey B., Descours, Anne, Barnett, Susan W., Srivastava, Indresh K., Martin, Loïc
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645002/
https://ncbi.nlm.nih.gov/pubmed/18835005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.039
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