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Association Mapping in Outbred Populations: Power and Efficiency When Genotyping Parents and Phenotyping Progeny

We develop expressions for the power to detect associations between parental genotypes and offspring phenotypes for quantitative traits. Three different “indirect” experimental designs are considered: full-sib, half-sib, and full-sib–half-sib families. We compare the power of these designs to detect...

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書誌詳細
主要な著者: Chenoweth, Stephen F., Visscher, Peter M.
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644963/
https://ncbi.nlm.nih.gov/pubmed/19087954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099218
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