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Association Mapping in Outbred Populations: Power and Efficiency When Genotyping Parents and Phenotyping Progeny

We develop expressions for the power to detect associations between parental genotypes and offspring phenotypes for quantitative traits. Three different “indirect” experimental designs are considered: full-sib, half-sib, and full-sib–half-sib families. We compare the power of these designs to detect...

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Detalhes bibliográficos
Main Authors: Chenoweth, Stephen F., Visscher, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644963/
https://ncbi.nlm.nih.gov/pubmed/19087954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099218
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