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Association Mapping in Outbred Populations: Power and Efficiency When Genotyping Parents and Phenotyping Progeny

We develop expressions for the power to detect associations between parental genotypes and offspring phenotypes for quantitative traits. Three different “indirect” experimental designs are considered: full-sib, half-sib, and full-sib–half-sib families. We compare the power of these designs to detect...

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Bibliografski detalji
Glavni autori: Chenoweth, Stephen F., Visscher, Peter M.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644963/
https://ncbi.nlm.nih.gov/pubmed/19087954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099218
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