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Chromatin Condensing Functions of the Linker Histone C-terminal Domain are mediated by Specific Amino Acid Composition and Intrinsic Protein Disorder

Linker histones bind to the nucleosomes and linker DNA of chromatin fibers, causing changes in linker DNA structure and stabilization of higher order folded and oligomeric chromatin structures. Linker histones affect chromatin structure acting primarily through their ~100 residue C-terminal domain (...

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Main Authors: Lu, Xu, Hamkalo, Barbara, Parseghian, Missag H., Hansen, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644900/
https://ncbi.nlm.nih.gov/pubmed/19072710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801636y
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