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Chromatin Condensing Functions of the Linker Histone C-terminal Domain are mediated by Specific Amino Acid Composition and Intrinsic Protein Disorder

Linker histones bind to the nucleosomes and linker DNA of chromatin fibers, causing changes in linker DNA structure and stabilization of higher order folded and oligomeric chromatin structures. Linker histones affect chromatin structure acting primarily through their ~100 residue C-terminal domain (...

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Detalhes bibliográficos
Main Authors: Lu, Xu, Hamkalo, Barbara, Parseghian, Missag H., Hansen, Jeffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644900/
https://ncbi.nlm.nih.gov/pubmed/19072710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801636y
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