Classical complement pathway activation by antipneumococcal antibodies leads to covalent binding of C3b to antibody molecules.

We have examined whether or not a physical relationship exists between antipneumococcal antibodies (Ab) and C3b when Ab activate the classical complement pathway on the surface of pneumococci (Pn). After sensitization with 125I-labeled Ab, Pn were sequentially incubated with purified C1, C4, C2, and...

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Pubblicato in:	Infect Immun
Autori principali:	Brown, E J, Berger, M, Joiner, K A, Frank, M M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1983
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6642644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.42.2.594-598.1983
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