Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice

BACKGROUND: Inflammation may contribute to the pathogenesis of various forms of pulmonary hypertension (PH). Recent studies in patients with idiopathic PH or PH associated with underlying diseases suggest a role for interleukin-6 (IL-6). METHODS: To determine whether endogenous IL-6 contributes to m...

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Hauptverfasser: Savale, Laurent, Tu, Ly, Rideau, Dominique, Izziki, Mohamed, Maitre, Bernard, Adnot, Serge, Eddahibi, Saadia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644669/
https://ncbi.nlm.nih.gov/pubmed/19173740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-6
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