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Effect of Pluronic P85 on Amino Acid Transport in Bovine Brain Microvessel Endothelial Cells

A synthetic amphiphilic block copolymer Pluronic P85 (P85) was shown to be among the most potent inhibitors of Pgp efflux system in the blood–brain barrier (BBB) and capable of enhancing delivery of Pgp substrates to the brain. The purpose of this work is to evaluate the effects of P85 on amino acid...

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Autors principals: Zhang, Xiaobin, Alakhova, Daria Y., Batrakova, Elena V., Li, Shu, Yang, Zhihui, Li, Yili, Kabanov, Alexander V.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644348/
https://ncbi.nlm.nih.gov/pubmed/18677571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-008-9119-1
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