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Tissue Inhibitor of Metalloproteinase-1 Deficiency Abrogates Obliterative Airway Disease after Heterotopic Tracheal Transplantation

Obliterative bronchiolitis (OB) is a major cause of allograft dysfunction after lung transplantation and is thought to result from immunologically mediated airway epithelial destruction and luminal fibrosis. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have be...

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Autori principali: Chen, Peter, Farivar, Alexander S., Mulligan, Michael S., Madtes, David K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644207/
https://ncbi.nlm.nih.gov/pubmed/16388023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0344OC
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