Smad3 Deficiency Ameliorates Experimental Obliterative Bronchiolitis in a Heterotopic Tracheal Transplantation Model

Chronic allograft rejection manifested as obliterative bronchiolitis (OB) remains the single greatest impediment to long-term survival after lung transplantation. Transforming growth factor-β1 (TGF-β1) has been implicated in the tissue remodeling response associated with OB. Therefore, its intracell...

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Autores principales: Ramirez, Allan M., Takagawa, Shinsuke, Sekosan, Marin, Jaffe, H. Ari, Varga, John, Roman, Jesse
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2004
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618624/
https://ncbi.nlm.nih.gov/pubmed/15466388
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