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Serotonin-Induced Growth of Pulmonary Artery Smooth Muscle Requires Activation of Phosphatidylinositol 3-Kinase/Serine-Threonine Protein Kinase B/Mammalian Target of Rapamycin/p70 Ribosomal S6 Kinase 1

We have previously found that both mitogen-activated protein kinase (MAPK)- and Rho kinase (ROCK)-related signaling pathways are necessary for the induction of pulmonary artery smooth muscle cell (SMC) proliferation by serotonin (5-hydroxytryptamine [5-HT]). In the present study, we investigated the...

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Detalhes bibliográficos
Main Authors: Liu, Yinglin, Fanburg, Barry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644181/
https://ncbi.nlm.nih.gov/pubmed/16195541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0163OC
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