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Tissue plasminogen activator modulates the cellular and behavioral response to cocaine

Cocaine exposure induces long-lasting molecular and structural adaptations in the brain. In this study, we show that tissue plasminogen activator (tPA), an extracellular protease involved in neuronal plasticity, modulates the biochemical and behavioral response to cocaine. When injected in the acute...

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Detalhes bibliográficos
Main Authors: Maiya, Rajani, Zhou, Yan, Norris, Erin H., Kreek, Mary Jeanne, Strickland, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644150/
https://ncbi.nlm.nih.gov/pubmed/19181855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812491106
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