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Tissue plasminogen activator modulates the cellular and behavioral response to cocaine

Cocaine exposure induces long-lasting molecular and structural adaptations in the brain. In this study, we show that tissue plasminogen activator (tPA), an extracellular protease involved in neuronal plasticity, modulates the biochemical and behavioral response to cocaine. When injected in the acute...

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Autors principals: Maiya, Rajani, Zhou, Yan, Norris, Erin H., Kreek, Mary Jeanne, Strickland, Sidney
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644150/
https://ncbi.nlm.nih.gov/pubmed/19181855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812491106
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