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Key role of tissue plasminogen activator in neurovascular coupling

The increase in blood flow evoked by synaptic activity is essential for normal brain function and underlies functional brain imaging signals. Nitric oxide, a vasodilator released by NMDA receptor activation, is critical for the flow increase, but the factors linking NMDA receptor activity to nitric...

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Detalhes bibliográficos
Main Authors: Park, Laibaik, Gallo, Eduardo F., Anrather, Josef, Wang, Gang, Norris, Erin H., Paul, Justin, Strickland, Sidney, Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242693/
https://ncbi.nlm.nih.gov/pubmed/18195371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708823105
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