E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors

Hematopoiesis is a tightly controlled process maintained by a small pool of hematopoietic stem cells (HSCs). Here, we demonstrate that the LT-HSC, MPP, premegakaryocytic/erythroid, Pre CFU-E, Pre GM, MkP, and granulocyte-macrophage compartments were all significantly reduced in E2A-deficient bone ma...

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Bibliografiska uppgifter
Huvudupphovsmän: Semerad, Craig L., Mercer, Elinore M., Inlay, Matthew A., Weissman, Irving L., Murre, Cornelis
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644141/
https://ncbi.nlm.nih.gov/pubmed/19181846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808866106
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