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Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r

The melanocortin-1 receptor (MC1R) is a key regulator of pigmentation in mammals and is tightly linked to an increased risk of skin cancers, including melanoma, in humans. Physiologically activated by α-melanocyte stimulating hormone (αMSH), MC1R function can be antagonized by a secreted factor, ago...

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Detalhes bibliográficos
Main Authors: Le Pape, Elodie, Passeron, Thierry, Giubellino, Alessio, Valencia, Julio C., Wolber, Rainer, Hearing, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644118/
https://ncbi.nlm.nih.gov/pubmed/19174519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806753106
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