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Integrin α(v)β(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress
Acutely secreted von Willebrand factor (VWF) multimers adhere to endothelial cells, support platelet adhesion, and may induce microvascular thrombosis. Immunofluorescence microscopy of live human umbilical vein endothelial cells showed that VWF multimers rapidly formed strings several hundred microm...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644087/ https://ncbi.nlm.nih.gov/pubmed/18927433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-158584 |
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