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Type 5 phosphodiesterase expression is a critical determinant of the endothelial cell angiogenic phenotype

Type 5 phosphodiesterase (PDE5) inhibitors increase endothelial cell cGMP and promote angiogenesis. However, not all endothelial cell phenotypes express PDE5. Indeed, whereas conduit endothelial cells express PDE5, microvascular endothelial cells do not express this enzyme, and they are rapidly angi...

詳細記述

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書誌詳細
主要な著者: Zhu, Bing, Zhang, Li, Alexeyev, Mikhail, Alvarez, Diego F., Strada, Samuel J., Stevens, Troy
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643995/
https://ncbi.nlm.nih.gov/pubmed/19028977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90474.2008
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