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PI3Kγ-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling
In this study, we have examined the role of phosphoinositide 3 kinase γ (PI3Kγ), a class Ib PI3K, in contributing to airway remodeling utilizing PI3Kγ-deficient mice exposed to chronic allergen challenge. Wild-type (WT) mice sensitized to ovalbumin (OVA) and chronically challenged with OVA for 1 mo...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643991/ https://ncbi.nlm.nih.gov/pubmed/19028980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90275.2008 |
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