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Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance
Mitochondria affect cerebrovascular tone by activation of mitochondrial ATP-sensitive K(+) (K(ATP)) channels and generation of reactive oxygen species (ROS). Insulin resistance accompanying obesity causes mitochondrial dysfunction, but the consequences on the cerebral circulation have not been fully...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643987/ https://ncbi.nlm.nih.gov/pubmed/19005015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90656.2008 |
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