ModuleMiner - improved computational detection of cis-regulatory modules: are there different modes of gene regulation in embryonic development and adult tissues?

We present ModuleMiner, a novel algorithm for computationally detecting cis-regulatory modules (CRMs) in a set of co-expressed genes. ModuleMiner outperforms other methods for CRM detection on benchmark data, and successfully detects CRMs in tissue-specific microarray clusters and in embryonic devel...

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Bibliographic Details
Main Authors: Van Loo, Peter, Aerts, Stein, Thienpont, Bernard, De Moor, Bart, Moreau, Yves, Marynen, Peter
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643937/
https://ncbi.nlm.nih.gov/pubmed/18394174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-r66
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