Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis

BACKGROUND: Epigenetic mechanisms regulate gene expression patterns affecting cell function and differentiation. In this report, we examine the role of histone acetylation in gene expression regulation in mouse embryonic stem cells employing transcriptomic and epigenetic analysis. RESULTS: Embryonic...

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Bibliografiske detaljer
Main Authors: Karantzali, Efthimia, Schulz, Herbert, Hummel, Oliver, Hubner, Norbert, Hatzopoulos, AK, Kretsovali, Androniki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643936/
https://ncbi.nlm.nih.gov/pubmed/18394158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-r65
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