Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis

BACKGROUND: Epigenetic mechanisms regulate gene expression patterns affecting cell function and differentiation. In this report, we examine the role of histone acetylation in gene expression regulation in mouse embryonic stem cells employing transcriptomic and epigenetic analysis. RESULTS: Embryonic...

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Detalhes bibliográficos
Main Authors: Karantzali, Efthimia, Schulz, Herbert, Hummel, Oliver, Hubner, Norbert, Hatzopoulos, AK, Kretsovali, Androniki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643936/
https://ncbi.nlm.nih.gov/pubmed/18394158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-r65
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