Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol

Cyclosporine A (CsA) is an efficient immunosuppressant used for reducing allograft rejection but with a severe side effect of causing hypertension. We hypothesize that the renal epithelial sodium channel (ENaC) may participate in CsA-induced hypertension. In the present study, we used the patch-clam...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Jing, Zhang, Zhi-Ren, Chou, Chu-Fang, Liang, You-You, Gu, Yuchun, Ma, He-Ping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2009
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643868/
https://ncbi.nlm.nih.gov/pubmed/19091785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90647.2008
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