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Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol
Cyclosporine A (CsA) is an efficient immunosuppressant used for reducing allograft rejection but with a severe side effect of causing hypertension. We hypothesize that the renal epithelial sodium channel (ENaC) may participate in CsA-induced hypertension. In the present study, we used the patch-clam...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643868/ https://ncbi.nlm.nih.gov/pubmed/19091785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90647.2008 |
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